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4307
Wanted: Eosinophils, Dead or Alive? Eosinophil Cell Death Subroutines and Implications for Eosinophil-Targeted Therapy
Monday, March 3, 2014: 10:45 AM-12:00 PM
Convention Center, Mezzanine Level, Room 16AB
1.25 CME/ 1.50 CE
Moderator:
Gerald J. Gleich , MD FAAAAI
Learning Objectives:
  1. Identify cell death subroutines
  2. Discuss consequences of eosinophils' dying by different subroutines
  3. Discuss consequences of cell death subroutines on efficacy and safety of eosinophil-targeting agents
10:45 AM
Eosinophil Extracellular DNA Trap Cell Death (ETosis) Mediates Lytic Release of Free Secretion-Competent Eosinophil Granules
Lisa A. Spencer, PhD FAAAAI
11:05 AM
Siglec-8 Engagement Induces Apoptotic or Lytic Eosinophil Cell Death, Depending on Cell Activation Status
Nives Zimmermann, MD FAAAAI
11:25 AM
Targeting Eosinophils in Disease
Parameswaran K. Nair, MD PhD FRCP
11:45 AM
Question & Answer
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