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Clinical and Environmental Factors Associated with Habitual Snoring in the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS)
Sunday, March 6, 2016: 4:45 PM
Concourse Foyer (Convention Center)
Jennifer A. Kannan, MD, Cole Brokamp, BS, David I. Bernstein, MD FAAAAI, James E. Lockey, MD MS FAAAAI, Manuel S. Villareal, MD FAAAAI, Gurjit K. Khurana Hershey, MD PhD FAAAAI, Grace K. LeMasters, PhD, Patrick Ryan, PhD
Rationale: Childhood snoring has been linked to hypertension, BMI, behavioral changes, and decreased school performance. 

Methods: Children born to atopic parents were enrolled in a prospective birth cohort. Participants completed clinical evaluations and questionnaires regarding allergic and respiratory symptoms, environmental exposures, and snoring frequency at ages 1-4 and 7. Snoring was categorized as never (< 1 night/week), sometimes (1-2 nights/week) and frequently (≥ 3 nights/week). Traffic pollution exposure (TRAP) was estimated using a land-use regression model. The association between early (< age 4) and current (age 7) allergic disease, environmental exposures, and snoring at age 7 was examined using proportional odds logistic regression.

Results: Of the 609 children analyzed the prevalence of sometimes and frequently snoring at age 7 was 40% and 21%, respectively. Early factors associated with age 7 snoring included dog ownership (OR= 1.38 [95% CI 1.00-1.92]), allergic rhinitis (OR=1.72 [95% CI 1.12-2.65]), wheezing (OR=2.30 [95% CI 1.36-3.91]), and breastfeeding (OR=0.72 [95% CI 0.53-0.99]). Current factors at age 7 associated with snoring included being obese (OR=1.69 [95% CI 1.17-2.44]), TRAP exposure (OR= 1.51 [95% CI 1.05-2.18]), eczema (OR=1.57 [95% CI 1.00-2.48]), wheezing (OR=2.58 [95% CI 1.68-4.00]), respiratory infections (OR=2.23 [95% CI 1.51-3.30]), and asthma (OR=1.97 [95% CI 1.28-3.05]).

Conclusions: Children with an early diagnosis of allergic rhinitis and wheezing are at increased risk for habitual snoring later in childhood. In addition, obesity, asthma, and TRAP exposure are more common among children with habitual snoring at age 7. These children should be considered for screening of sleep disorders.