Case of a Young Man with Anaphylaxis to Hempseeds (Cannabis sativa).
Sunday, March 6, 2016
South Exhibit Hall H (Convention Center)
Vaishaali Manga, MD, D. William Moote, MD FAAAAI

Anaphylaxis to hempseed is uncommonly documented in the current literature. We present a case of a 21 year-old man who developed abdominal pain, angioedema of the lip, facial swelling and respiratory distress within fifteen minutes of consuming a smoothie with hemp seeds, grapes, strawberries, mango, pineapple, blueberries, cucumber, spinach and kale. The patient was treated with epinephrine auto-injector and improved within thirty seconds. Approximately fifteen minutes later, upon arrival to the ER, he had an episode of emesis. The patient has smoked and continues to smoke marijuana without any symptoms.


Consultation with the patient obtaining a detailed history followed by physical examination and skin prick test to an environmental panel and foods including hemp seeds, blueberries, spinach, grapes almonds and apples.


Skin prick test was positive to freshly ground hemp seeds with a reaction of a 10 mm wheal and 32 mm of erythema. Other foods tested were negative, except almond with a reaction of 4 mm wheal and 10 mm erythema; although he consumes almond milk on a daily basis without any symptoms. From the environmental panel, the patient tested positive to dust mites, cockroach, box elder tree, grass, ragweed and cat.


Reported cases of anaphylaxis to hempseeds are very rare, with the last case being reported in 2003. Furthermore, we find it very interesting that despite his anaphylaxis to hempseeds, he is still able to smoke marijuana without any respiratory symptoms.