More than a million people suffer from food allergies in Spain. But the prevalence of fruit allergy may vary from one geographical area to another, regarding dietary habits and palynology area. The aim of this work was to know the differences in the clinical and immunological profile of patients allergic to fruits in different parts of Spain compared to Alicante in the east of Spain.
A cross-sectional study was performed selecting patients from allergy services of six Spanish hospitals. A detailed history, skin tests with fresh fruits and standardized extracts, and serum samples were obtained from patients with suspected allergy to fruits. Allergen components were studied by ImmunoCAP ISAC Specific IgE (Phadia Spain- Thermofisher).
213 patients diagnosed of fruit allergy were enrolled. Oral syndrome, dermal, respiratory, digestive symptoms and anaphylaxis were produced mainly by peach, melon, apricot, apple, cherry and kiwi in this order. Patients allergic to fruits showed an average of 3.6 sensitizations to different pollens, being the most frequent Plantago L., olives, grasses and Artemisia. Pru p 3 followed by Act d 2 were found the major allergens for most symptoms to fruits in the east of Spain.
The clinical and immunological profile of fruit allergy patients from east of Spain differs from other regions studied in their sensitization to fruits, pollens and allergen components.