The baseline series (BS) of patch tests include those allergens considered to be frequent cause of allergic contact dermatitis (ACD). In a previous study we analyzed and compared different European BS.
We analyzed the BS used in 2015 in different countries (EEUU, Brazil, China, Japan, India, Korea and Australia), geographic areas (Europe, Latin-America) and the International Contact Dermatitis Group (ICDRG) BS.
The analysed batteries include different 119 allergens. The minimal BS of the ICDRG includes 32 allergens and the extended one 87. The number of substances range between 24 (Japanese BS) and 60 (Australian and Chinese BS), mean 38.
Only eleven allergens (9%) are present in all BS: PTB formaldehyde, cobalt, colophonium, formaldehyde, Peru balsam, nickel, chrome, p-phenylendiamine and the fragrance I, paraben and thiuram mixes.
Another six haptens appear in almost all BS: mercaptobenzothiazole (except Japanese), epoxy resin (except Korean), mercapto mix (except Brazilian), kathon CG (except Indian), neomicine (except Chinese) and quaternium-15 (except Indian and Japanese).
Forty allergens (33.6%) are present only in one BS: 12 in Australian, 10 in Chinese, 6 in Brazilian, 3 in Latin-American, Indian and Japanese and one in the North American BS.
The concentrations used varied in 18 substances (15%).
There are important differences between the different BS, in the number of tested substances, in their composition and in the concentrations used.
The variations regarding BS components used are probably in relation to the different occupational activities, usual topical drugs used, use or not of mixes substances and in recent studies.