Methods: Patients with physician-diagnosed CRS on topical medications other than saline alone were recruited from an Allergy Clinic. Claims data were obtained from patient pharmacies for the 6 months prior to enrollment and medication possession ratio (MPR) was calculated. A telephone survey was conducted to assess barriers to adherence using an adaptation of the Brief Medication Questionnaire (BMQ). Patients were defined as non-adherent if they self-reported missed doses for one or more days in the week prior to survey.
Results: Thirteen patients, age 35 to 77, were enrolled. Based on data obtained from the BMQ, 61.5% were non-adherent to their medications in the past week. The mean 6-month MPR; however, based on pharmacy refill data, was 81.5%. Three of the thirteen patients were unsure whether the medication was effective indicating a belief barrier. Approximately half of patients were positive for recall barrier; most patients with recall barriers reported the medication as inconvenient to use or time-intensive to prepare. Access barriers were present in five patients with reasons including expense and inability of the preferred pharmacy to provide the specific medication.
Conclusions: Adherence to topical medications for CRS is low. Attempting to identify and decrease belief, recall, and access barriers is crucial for management of CRS.