Clinical and Epidemiological Differences in Patients with Acute Urticaria and Chronic Urticaria
Saturday, March 5, 2016
South Exhibit Hall H (Convention Center)
Mehtap Haktanir Abul, MD, Fazil Orhan, Zekiye Ilke Kilic Topcu, Taner Karakas, Ali Baki
Rationale: Urticaria is commonly seen and it is difficult to determine the etiologic factors in children. The aim of the study is to define different clinical patterns of urticaria in childhood.

Methods: This is a prospective study included the children who were referred to our clinic for evaluation of urticaria. Laboratory tests including serologic, autoimmune, and allergic analyses were conducted

Results: One hundred and eighty two children (90 females and 92 males) were evaluated. The age range was 4 month- 17 years old.  Of the cases, 58.2 % (n=106) were diagnosed with acute urticaria and 41.8 % (n=76) were diagnosed with chronic urticaria. There wasn’t any significant difference in gender between acute and chronic urticaria group. The median age was 5 years (range: 4 month- 16 years old) and 6.5 years (range: 7 month- 17 years old) for acute and chronic urticaria groups respectively. CRP, IgE, eosinophil, C3 and C4 levels are higher in acute urticaria than chronic urticaria patients that were not statistically significant. Physical urticaria was commonly seen in children with chronic urticaria (48.7%). Spontaneous resolution is more frequently seen in acute urticaria patients than the chronic urticaria patients (p=0.016)

Conclusions: There are clinical and epidemiological differences in patients with acute urticaria and patients with chronic urticaria. Recurrence, spontaneous resolution seems to be the factors associated with the differences in both group of patients. Physical urticaria is commonly seen and should be questioned in children with chronic urticaria