Late Breaking Poster Session

L1

Potential Role of Gut Microbial Metabolites in Allergy Prevention in Children
Caroline Roduit Remo Frei Ruth Ferstl Susanne Loeliger Charlotte Braun-Fahrländer Erika Von Mutius, MD MSc Juha Pekkanen, MD Jean-Charles Dalphin Josef Riedler Roger Lauener, MD Liam O'Mahony, PhD

L2

Associations of Early Life Exposures and Environmental Factors with Asthma Among Children in Rural and Urban Areas of Guangdong, China
Jing Li, MD MSc Zhao Wei Yang, PhD Mulin Feng Marjut Roponen Bianca Schaub Gary Wing-kin Wong, MD, FRCPC

L3

Austri, a Large Randomized Study in Adolescents and Adults with Asthma, Assessing the Safety and Efficacy of Salmeterol in Combination with Fluticasone Propionate Compared to Fluticasone Propionate Alone
David A. Stempel, MD FAAAAI Ibrahim Raphiou, PhD Kenneth Kral Anne Yeakey Kathy Buaron Amanda Emmett Charlene M. Prazma, PhD Steve Pascoe, MD

L4

The Diagnostic Testing Accuracy of Urinary Leukotriene E4 in Determining Aspirin Intolerance in Asthma: A Systematic Review and Meta-Analysis
John B. Hagan, MD FAAAAI Tanya M. Laidlaw, MD Rohit D Divekar, MBBS, PhD Erin O'Brien, MD Hirohita Kita, MD Gerald W. Volcheck, MD FAAAAI Christina R. Hagan Devyani Lal, MD Harry G. Teaford, MD Patricia J. Erwin Matthew A. Rank, MD FAAAAI

L5

Factors Affecting Control and Adherence to One Year Treatment in Elderly Asthmatics in Turkey
Bilun Gemicioglu, M.D.,Ph.D. Hasan Bayram, M.D.,Ph.D. Arif Cimrin, M.D. Oznur Abadoglu, M.D. Aykut Cilli, M.D. Esra Uzaslan, M.D. Hakan Gunen, M.D. Levent Akyildiz, M.D. Mecit Suerdem, M.D. Tevfik Ozlu, M.D. Zeynep Misirligil, M.D.

L6

Comparison of Omalizumab Therapy Effectiveness in Patients with Hypersensitivity to Non-Steroidal Anti-Inflammatory Drugs (NSAID) and Patients Who Tolerate NSAID (non-NSAID) – Polish Real Life Experience
Izabela R. Kuprys-Lipinska, MD PhD Pawel Majak, MD PhD Joanna Molinska, M. Sc. Mateusz Jonakowski, Student Piotr Kuna, MD PhD

L7

Role of Home Environmental Staphylococcus Aureus Bacterial Allergens in Childhood Asthma
Meghan F. Davis, DVM, MPH, PhD Shanna Ludwig, PhD Emily Brigham, MD Meredith C. McCormack, MD Elizabeth Matsui, MD MHS

L8

Environmentally-Induced Epigenetic Changes Correlate with Race and Childhood Asthma Severity
Marcia A. Chan, PhD Christina E. Ciaccio, MD MSc FAAAAI Nicole M Gigliotti, BS Mo Rezaiekhaligh, MS Jacob A Siedlik, MA Kevin Kennedy, MPH CIEC Charles S. Barnes, PhD FAAAAI

L10

Mepolizumab in COPD with Eosinophilic Bronchitis: A Randomized Clinical Trial
Parameswaran K Nair, MD PhD FRCP FRCPC Angira Dasgupta, MD Melanie Kjarsgaard, RRT Dante Capaldi, BSc (Hon) Katherine Radford, MSc Fernando P Aleman, MD Grace Parraga, PhD Paul M. O'Byrne, MB, FRCPC, FRSC

L11

Role of R213G Polymorphism in Airway HYPER-Responsiveness
Rohit Gaurav, MSc, PhD Brittany Hartman, BS Jason Varasteh, BS Hong-wei Chu, MD Russell P Bowler, MD, PhD

L12

Prostaglandin E2in Induced Sputum Following Oralaspirin Challenge in Asthma Patients with and without Aspirin Hypersensitivity
Lucyna Mastalerz, MD, PhD Maria Ignacak, MD Michal Buczek, MD Aleksandra Cholewa, MD Natalia Celejewska-Wojcik, MD Krzysztof Wojcik, MD, PhD Anna Gielicz, MSc Krzysztof Oles, MD, PhD Marek Sanak, MD,PhD

L13

A New Pharmacological Approach for Asthma through Tissue-Specific Modulation of the GABA(A) Receptor
Leggy A. Arnold, PhD Gloria S. Forkuo, PhD Amanda N. Nieman Olivia B. Yu Margaret L. Guthrie Nina Y. Yuan Revathi Kodali Rajwana Jahan Charles W Emala James M. Cook, PhD Douglas C. Stafford, PhD Mitchell H. Grayson, MD FAAAAI

L14

Role of Circulating ICOS+ Follicular Helper T Cells in the Pathogenesis of Birch Pollen Allergy
Ryuta Kamekura Koji Kawata Sumito Jitsukawa Tomonori Nagaya Keiji Yamashita Fumie Ito Kenichi Takano Katsunori Shigehara Tetsuo Himi Shingo Ichimiya

L15

Case Report of a Previously Unreported Type of DOCK8 Deficiency
Stephen Dinetz, MD Betty B. Wray, MD FAAAAI

L16

Immune Phenotype in Children with Mitochrondial Disease
Dat Q. Tran, MD, FAAAAI Jessica Bunn Rocio Vaglienty-Pena Melissa S. Knight Noemy Y. Contreras Rahmat B. Adejumo Syed S. Hashmi Mary K. Koenig

L17

Evaluation of Serum Levels of Osteopontin and IgG Anti-Osteopontin Autoantibodies As Potential Biomarkers of Immune Activation in Patients with Allergic Diseases
Elisa Villa, MD Rosalba Minisini Olaf Rötzschke Kia Joo Puan Boris Buenbrazo San Luis Anand Andiappan Nausicaa Clemente Luca Gigliotti Elena Boggio Annalisa Chiocchetti Umberto Dianzani Mario Pirisi

L18

Patient-Reported Outcomes (PROs) in Patients Receiving Omalizumab (OMB): A Systematic Literature Review
Ashok V. Vegesna, PharmD Reynold A Panettieri, MD Susan Gabriel, MSc Kimberly M. Ruiz, EdM Jennifer A. Colby, PharmD Brett Maiese, PhD, MHS Jonathan Corren, MD

L19

Epicutaneous Allergen Exposure Dose Determines Manifestation of Allergic Airway Disease in Mice
Tarandeep Singh Daniel M. Moldaver Christopher D Rudulier, PhD Jennifer Wattie Mark Larché, PhD

L20

Analysis of Home Dust for Allergens Related to Staphylococcus Aureus
Shanna Ludwig, PhD Isabel Jimenez-Bush Emily Brigham, MD Sonali Bose Gregory B. Diette, MD MHS Meredith C. McCormack, MD Elizabeth Matsui, MD MHS Meghan F. Davis, DVM, MPH, PhD

L21

Risk Factors for Childhood Peanut Allergy in a Large Birth Cohort Study: Growing up in New Zealand
Colleen R. McMilin Cameron Grant Susan M. B. Morton Carlos Camargo Jr., MD, DrPH

L22

Increased Cis-to-Trans Urocanic Acid Ratio in the Skin of Chronic Urticaria Leads to the Enhancement of Mast Cell Degranulation
Young-Min Ye, MD Duy Le Pham Hae-Sim Park, MD FAAAAI Donald Y.M. Leung, MD PhD FAAAAI Kyung-Min Lim

L23

Multicenter Study of Food Induced Anaphylaxis in Korean Infants
You Hoon Jeon, MD Soo-Young Lee , MD Kang Mo Ahn, MD So-Yeon Lee, MD Kyung Won Kim, MD Hyun Hee Kim, MD Jeong Hee Kim, MD Hye Young Yum, MD Woo Kyung Kim, MD Yong-Mean Park, MD Tae Won Song, MD Jihyun Kim, MD Yong Ju Lee, MD Gwang Cheon Jang, MD Kyoung Uk Jeong, MD Yoon Hee Kim, MD Taek Ki Min, MD Bok Yang Pyun, MD

L24

Proteomic Profiling of Atopic Dermatitis, Psoriasis, and Contact Dermatitis Patients
Jingya Wang Mayte Suarez-Farinas, PhD Yeriel Estrada James G. Krueger, MD PhD Melissa Parker Emma Guttman-Yassky, MD PhD Michael D. Howell, PhD

L25

Efficacy and Safety of Crisaborole Topical Ointment, 2%, a Novel, Nonsteroidal, Topical, Anti-Inflammatory, Phosphodiesterase Inhibitor in 2 Phase 3 Studies in Children and Adults with Mild-to-Moderate Atopic Dermatitis
Mark Boguniewicz, MD FAAAAI Amy S Paller Wynnis L Tom Mark G Lebwohl Robin L Blumenthal Robert S Call Lawrence F Eichenfield Douglass W Forsha William C Rees Eric L Simpson, MD, MCR Linda F Stein Gold Andrea L Zaenglein Matty H Hughes Lee T Zane Adelaide A Hebert

L26

The Negative Impact of Persistent Penicillin Allergy Labeling
Kali Gerace, MD Li Wang, MS Elizabeth J. Phillips, MD

L27

Skin Testing for the Diagnosis of Severe Perioperative Anaphylaxis to Clindamycin
Alberta L. Wang, MD Laura B. Fanning, MD

L28

Antibiotic Allergy De-Labeling: Teaching an Old Dog New Tricks
Jason A. Trubiano, MD Susan E Beekmann Phillip M Polgren Leon J Worth M L Grayson Elizabeth J. Phillips, MD

L29

The Use of Drug Desensitization Protocols at a Pediatric Institution
Malika Gupta, MD Jamie M Gomes, PharmD, BCPS Jamie Sklar, RN, BSN, MS, CCRN-K Sigrid Payne DaVeiga, MD

L30

Early Introduction of Dietary Egg Reduces Egg Sensitization at 12 Months of Age in Infants at Risk of Allergic Disease
John Wei-Liang Tan, MD, FRACP Carolina Valerio, BN (hons) Elizabeth H Barnes, BAppSc, MStat Peter P Van Asperen, MD,FRACP,PhD Alyson Margaret Kakakios, MD, FRACP Dianne E. Campbell, MD, FRACP, PhD BEAT Study Group

L31

Correlation of Negative Tree Nut Skin-Prick Tests and Successful Tree Nut Food Challenges Among Peanut-Allergic Children
Inderpal Randhawa, MD Christopher P. Parrish, M.D. Tricia Morphew, MSc

L33

Cor a 14 Specific Ig E Best Distinguishes Between Hazelnut Allergic and Tolerant Patients
Ana Alvez, MD Elsa Phillips-Angles, MD Maria Pedrosa, MD Teresa Boyano-Martinez Sr., MD Carmen Garcia-Ara, MD, PhD T. Caballero, MD PhD Santiago Quirce, MD PhD

L34

Resolution of Severe Near Fatal Food Allergy Following Hematopoietic Stem Cell Transplantation
Ryan Sinit, BS Clifton T. Furukawa, MD Sara Ratliff, ARNP Daniel H Petroni, MD PhD

L35

Population-Based Study Suggests Strong Genetic Association Between Eosinophilic Esophagitis and Asthma
Hannah Duffey, MD Kathryn Peterson, MD Rafael Firszt, M.D., M.B.A.

L36

Molecular Sensitization Pattern Profile in Proton Pump Inhibitor-Responsive Esophageal Eosinophilia Vs Proton Pump Inhibitor-Nonresponsive Eosinophilic Esophagitis (EoE) in Adult Patients
Marina Lluncor, MD Maria Pedrosa, MD Nataly Cancelliere, MD Daniela Rivero, MD Aurora Burgos, MD Ana Fiandor, MD Santiago Quirce, MD, PhD Teresa Caballero, MD PhD

L37

A Trial of an Oral CRTH2 Antagonist in Antihistamine-Refractory Chronic Spontaneous Urticaria
Eric Oliver, MD Kristin Chichester, MS Kelly Devine, RN Patricia M. Sterba, MS Craig Wegner, PhD Becky Vonakis, PhD FAAAAI Sarbjit S. Saini, MD FAAAAI

L38

BCX7353, a Potent Inhibitor of Plasma Kallikrein, Shows Sustained Maximal Enzyme Inhibition When Dosed Orally Once Daily: Results from a Phase I Trial in Healthy Subjects
Melanie Cornpropst Sylvia Dobo Jo Collier Angela Rose Ramanda Wilson YS Babu Phil Collis William Sheridan

L39

House Dust Mite Major Allergens Contributes Significantly to Specific IgG4 Response during Allergen Immunotherapy
Jianjun Chen, MD Yiwen You, MD Yue Zhou, MD Yanjun Wang, MD Weijia Kong, MD

L40

Altered TGF-Î² Signalling in Inflammatory Nasal Polyps Drive Remodelling in Crswnp
Nara Orban, MD Aarif Eifan, MD Mikila Jacobson, PhD Stephen R. Durham, MA MD FRCP

L41

Real-Life Study on the Effect of Micronized Cellulose Powder As Add-on to Intranasal As-Needed Treatment of Subjects with Pollen Allergic Rhinitis
Todor A. Popov, MD, PhD Anna Valerieva, MD Martin K. Church, MPharm, PhD, DSc Maria Staevska, MD, PhD Tanya Kralimarkova, MD, PhD Elena Petkova, MD Elitsa Valerieva, MD Tsvetelina Lazarova, MD Vasil Dimitrov, MD, PhD

L42

Distinct and Common Gene Expression Profiles of Nasal Polyp Tissues in Eosinophilic and Non-Eosinophilic Chronic Rhinosinusitis
Naoko Okada, PhD Tsuguhisa Nakayama, MD Daiya Asaka, MD Akio Matsuda, PhD Hirohisa Saito, MD PhD FAAAAI Mamoru Yoshikawa, MD Kenji Matsumoto, MD, PhD

L43

IgG4 Drives M2 Macrophages to Cortisol, Lcn-2 and IL-10 Release: Implications in Maintenance of Tolerance and Allergen Immunotherapy
Erika Jensen-Jarolim, MD Franziska Roth-Walter, PhD, Ass.Prof. Luis F. Pacios, PhD Stefanie Wagner, MSc, BSc Lisa-Maria Glenk Gerlinde Hofstetter, MSc, BSc Rupert Palme, PhD Georg A Roth, MD Karin Hufnagl, PhD Rodolfo Bianchini, PhD

L44

Facilitated Allergen Binding (FAB) Is a Meaningful Immunological Biomarker for Monitoring Immediate Clinical Efficacy in Short-Term Peptide Allergen Immunotherapy
Silke Allekotte, PhD Mohamed H. Shamji, PhD FAAAAI Gregor V. Zadoyan, PhD Elena M. Kasche Kija Shah-Hosseini, PhD Anatoli Astvatsatourov, PhD Sabine Pirotton, PhD Adrian Caplanusi, MD, PhD Stephen R. Durham, MA MD FRCP Ralph Mosges, MD FAAAAI

L45

Safety of STG320 Sublingual Tablets of House Dust Mite Allergen Extracts in Subjects with HDM-Associated Allergic Rhinitis: Results of a Pooled Analysis
Pascal M. Demoly, PhD, MD Karl-Christian Bergmann, PhD, MD Sandrine Khairallah, MSc Kathy Abiteboul, PharmD Robert K. Zeldin, MD

L46

Immunological Effects of Treatment with STG320 Sublingual Tablets of House Dust Mite Allergen Extracts in Subjects with HDM-Associated Allergic Asthma
Martine Le Gall Pascal M. Demoly, PhD, MD Patricia Rodriguez Angélique Racaud, MSci Robert K. Zeldin, MD

L47

Clinical Development Strategy for Unmet Need in Grass Subcutaneous Immunotherapy
Tim Higenbottam

L48

Eassi Survey: European Multicentre Prospective Study to Collect Systemic Adverse Reactions Due to Allergen Immunotherapy: Pediatric Population Results
Pablo Rodriguez Del Rio Carmen Vidal, MD PhD Jocelyne Just, MD PhD Oliver Pfaar, MD Pascal M. Demoly, PhD, MD Moises A. Calderon, MD PhD

L49

Molecular Fingerprinting of Complex Allergoids
Matthew Heath Andrew Bell Murray Skinner Alan D. Bullimore

L50

Patterns of Interferon Regulatory Factor 1 (IRF1) Expression By Respiratory Epithelial Cells Reveal Non-Redundancy of Type I Versus Type III Interferons
Ronald L. Rabin, MD Hilary Novatt Terence C. Theisen Lynnsey A. Renn

L51

IgE Cross-Linking Directly Modulates Degranulation and Tslpr Induction upon Food Allergen Challenge
Michelle T. Graham, Ph.D.

L52

Novel Noninvasive Biomarker for Eosinophilic Esophagitis (EoE)
Anil Mishra, PhD FAAAAI Sathisha Upparahalli Venkateshaiah, PhD Chandrashekara Puthanapura Mahadevappa, PhD Murli Manohar Alok Kumar Verma, PhD Jochen Mattner

L53

IL-33 Induces Eicosanoid Formation in Mast Cells By a Novel COX-1-Dependent Mechanism
Dingxin PAN Kathleen M. Buchheit, MD Tanya M. Laidlaw, MD FAAAAI Joshua A. Boyce, MD FAAAAI

L54

Development of a Germ-Free Murine Model for Prediction of Food Allergen Potency: Preliminary Studies Using Peanut Ara h1 and Ara h2 As Model Food Allergens
Nathan L. Marsteller, PhD Kwame Andoh-Kumi, MS Stef J Koppelman, PhD Richard E. Goodman, FAAAAI Joe L. Baumert, PhD

L55

Development of Multiple Features of Antigen-Induced Asthma Pathology in a New Strain of Mast Cell Deficient BALB/c-Kit^W-Sh/W-Sh Mice
Joseph D. Hernandez, MD PhD Mang Yu, MD PhD Riccardo Sibilano, PhD Mindy Tsai, DMSc Stephen J. Galli, MD

L56

In Vitro Induction of Peanut-Specific Tr1 Cells
Laurence Pellerin, PhD Jennifer Anne Jenks R. Sharon Chinthrajah, MD Arram Noshirvan Kari C. Nadeau, MD PhD FAAAAI Maria Grazia Roncarolo, MD Rosa Bacchetta, MD

L57

Binding of the Active Vitamin A Metabolite Retinoic Acid to the Major Cows Milk Allergen Bos d 5 Down-Regulates T-Cell Responses
Stefanie Wagner, MSc, BSc Karin Hufnagl, PhD Luis F F Pacios, PhD, Prof. Franziska Roth-Walter, PhD, Ass.Prof. Rodolfo Bianchini, PhD Gerlinde Hofstetter, MSc, BSc Erika Jensen-Jarolim, MD

L9.1

Increased Nasal Plasmacytoid Dendritic Cells Are Associated with Recurrent Wheezing Following Severe RSV Bronchiolitis
Maleewan Kitcharoensakkul, MD Leonard B. Bacharier, MD FAAAAI Huiqing Yin-Declue, PhD Toni Schweiger Charles W. Goss Jonathan S Boomer, PhD Geneline Sajol Kenneth Schectman Mario Castro, MD MPH