METHODS: A prospective study in patients 8-16 years of age. Patients were integrated into three groups according to the presence or absence of obesity and/ or overweight according to their anthropometric measurements of BMI using reference tables of the World Health Organization (WHO), After complete medical history a spirometry was performed according to the standards of the American Thoracic Society (ATS); after first spirometry, nebulized albuterol was administered, a second spirometry was performed.
RESULTS: 182 patients, mean age were 10.23±2.4 years old, classification after BMI assessment were: 60 obese (BMI 29.03±4.3kg/m2), 56 overweight (BMI 22.4±2.6kg/m2) and 66 eutrophic (BMI 17.4±2.1kg/m2), no significant differences in FEV1 baseline quantification in the three groups, the mean FEV1: Obese 2.33±0.63 l/sec, Overweight 2.43 ±0.89 l/sec and eutrophic 2.35±0.89 l/sec. After assessing bronchial reversibility in the second spirometry there were differences in the 3 groups in the variability percentage: obese, average 13.43±11.2%, overweight 7.7%±5.6% and 6.11±5.46% in eutrophic. There were statistically significant differences when comparing eutrophic with obese patients (p=0.018).
CONCLUSIONS: Over 23% of obese patients had asymptomatic presence of bronchial obstruction at the time of the study, significant differences with eutrophic patients. Comparing data published in obese asthmatic patients with our non-asthmatic obese patients show a similar FEV1 and percentages in the variability, which could hypothesize a "degree" of asymptomatic bronchial obstruction.