199:
A Comparison of Clinical Manifestations between Childhood and Adult Onset Shrimp Allergy
Saturday, March 3, 2018
South Hall A2 (Convention Center)
Jintana Chataroopwijit, MD, Pantipa Chatchatee, MD, Pornphan Paurika, MD, Jaichat Mekaroonkamol, MD, Jarungchit Ngamphaiboon, MD, Narissara Suratannon, MD
RATIONALE: Shrimp allergy is one of the leading causes of food-induced anaphylaxis. It seemed to indicate as a long lasting disease. Onset of shrimp allergy can start during either childhood or adulthood. Only few studies have described the natural course of shrimp allergy.

METHODS: We sought to determine and compare clinical manifestations of shrimp allergic subjects who develop symptoms before and after 18 years of age. Subjects with physician-diagnosed shrimp allergy follow up at the out-patient clinic during 2009-2016 were enrolled. Childhood and adult onset shrimp allergy were defined according to the onset of shrimp reaction before and after the age of 18 years.

RESULTS: There were 100 subjects with a definite diagnosis of shrimp allergy. Eighty subjects had first shrimp reaction during their childhood period while 20 subjects started to have shrimp allergic symptoms while they were adult. Subjects with childhood onset shrimp allergy were predominately male while most of adult onset populations were female. The most common coexist atopic disease is allergic rhinitis. One-third of subjects in both groups experienced anaphylaxis upon shrimp exposure. Nine percent of childhood onset group developed shrimp reaction on first shrimp exposure. Twenty percent of childhood onset and 40 percent of adult onset shrimp allergy have less severe upon subsequently shrimp exposure. Interestingly, 4% of childhood onset shrimp allergy was outgrown.

CONCLUSIONS: Shrimp allergy usually started in childhood period. Onset of shrimp allergy did not affect the severity of allergic symptoms. Significant numbers of subjects reported to have less severe reaction or resolved over time.