404:
Indoor Airborne Particles and Dust Aeroallergen Level
Sunday, March 4, 2018
South Hall A2 (Convention Center)
Freddy Pacheco, MS, Luke Gard, Ryan Allenbrand, Eric Bowles, Kevin Kennedy, MPH CIEC, Anita DiDonna, Jay M. Portnoy, MD FAAAAI, Charles S. Barnes, PhD FAAAAI
RATIONALE:

Airborne aeroallergens are usually thought to be particles themselves or to be adsorbed onto particles. Their deposition in house dust therefore should be a function of the airborne particles in a house. To examine the relationship of airborne particles and dust aeroallergen levels we performed the following.

METHODS: Data was from homes that were part of the Healthy Homes Study in Kansas City, Missouri. Full data was available for 79 homes. Airborne particle measurements and house dust was taken in the bedrooms of the pediatric asthmatics enrolled in the study. Airborne particles were monitored using a ARTI HHPC-6 Laser particle counter set to enumerate particles in 5 size ranges. Dust borne aeroallergen levels were determined for Feld1, Canf1, Musm1, Derf1, Derp1, Blag1, Alternaria, Aspergillus, Cladosporium and Penicillium. Spearman correlation analysis was performed using SPSS statistical software.

RESULTS:

Total airborne particles in the bedroom ranged from 171,745,000 to 1,060,000 per liter with a mean of 14,612,000 and a median of 5,552,000. Aeroallergen levels ranged to over 4 ug/g for pet and arthropod allergens and over 20 ug/g for fungal antigens. Alternaria, Cladosporium and Penicillium fungal antigen levels correlated positively with total particle levels as did Cat, Dog, Mouse and Dust Mite. Correlations were most significant for Mouse with the 2.0-5.0 um particle size and for Aspergillus with the 5.0-10.0 um size (p<0.5).

CONCLUSIONS:

Our data support the hypothesis that there is a relationship between indoor airborne particles and aeroallergen concentrations in house dust.