757:
Dust Mite Sensitization in Shrimp Allergic Pediatric Patients in the Midwest
Monday, March 5, 2018
South Hall A2 (Convention Center)
Salman A. Aljubran, MD, Charles S. Barnes, PhD FAAAAI

RATIONALE: Positive IgE to dust mite can be seen in up to 20% of patients with shrimp allergy. This percentage varies with geographic location. Dust mite sensitization in shrimp allergic pediatric patients in the Midwest is not known.

METHODS: Laboratory results of 483,490 specific IgE evaluations were reviewed to identify patients with positive IgE to shrimp. IgE determinations were performed from the year 2000 to 2015 on pediatric patients, ages 0.5 to 18 years, using the ThermoFisher ImmunoCap instrument. A test was considered positive when specific IgE values were greater than 0.35 kU/L.

RESULTS: 36,431 individual patients were identified. Of those, 7,946 patients had shrimp IgE levels checked. Out of these, 1,990 patients had positive IgE level (>0.35) to shrimp. Of the 1990 shrimp positive patients, 843(42%) had positive IgE to either D. farinae or D. pteronyssinus. Of those, 437 (22%) patients were positive to both types of dust mites. 386 (19%) patients were positive to D. farinae only while 12(0.6%) patients were positive to D. pteronyssinus alone.

CONCLUSIONS: There is a higher rate of sensitization to dust mite among shrimp allergic pediatric patients in the Midwest US. Also, shrimp allergic patients have higher rates of sensitization to D. farinae than D. pteronyssinus.