METHODS: Patients with asthma actively enrolled with a sensor and the Propeller Health platform for 8 or more weeks were included after their first use of a controller medication. The prescribed medication and recommended dosing schedule were recorded. Patient adherence to these recommendations were studied including patterns of adherence by age, time of day, and season.
RESULTS: The analysis included 1394 participants with 11,155 patient/weeks of data. Medication adherence incrementally improved by advancing age group with mean weekly adherence of 40.7% for those 12-25 years of age and 65% for 60+. The differences were statistically significant p <0.001. Adherence for those <12 was 47%, possibly reflecting parental assistance. Adherence was highest in the winter months for adults and fall/ winter for those <18. Adherence declined in the summer months, with reduction greatest in children from a peak of 52-54% in fall and winter months to 35% in July. Most patients (70%) were prescribed twice daily dosing with 56% adhering to both doses and 22% to either the AM or PM dose only. Mean adherence for combination ICS/LABA was 15% higher than ICS monotherapy.
CONCLUSIONS: Patterns of controller medication adherence varies by age, time of day, and season for patients with asthma. Such insights should play a pivotal role in developing personalized programs to improve adherence among adults and children with asthma.