658:
A Novel Photo-electrochemical Oxidation Air-Purification Technology Reduces Asthma Symptoms
Monday, March 5, 2018
South Hall A2 (Convention Center)
Nikhil Rao, MD, Yogi Goswami, PhD, Ambuj Kumar, MD, M.P.H, Jenny Wong, MS, Stephen B. Liggett, MD
RATIONALE: Photo-electrochemical oxidation (PECO) is a novel air purification technology developed to reduce circulating air pollutants. In addition to physical filtration, a photo-electrochemical reaction takes place on the surface of a nano-coated filter leading to the oxidation of organic matter. PECO can destroy particulate matter as small as 0.1nm that would otherwise not trapped by a HEPA filter. We hypothesized that with daily use, the portable PECO device would reduce asthma symptoms after 4 weeks of use.

METHODS: The study was performed among 18 individuals with self-reported asthma symptoms. Asthma symptoms were recorded on a 0 (minimum)-4 (maximum) point scale at baseline and at 4 weeks with elements including daily puffs of inhaler, sleep quality, interference with daily activities and control of asthma as per the ATAQ scale.

RESULTS: 16/18 individuals (89%) provided all survey data at baseline and at 4 weeks. There was a statistically significant change in asthma symptoms from baseline to those seen at four weeks (2.06 at baseline and 0.75 post intervention) resulting in a mean difference of 1.31(95% CI 0.45 to 2.18; p=0.006).

CONCLUSIONS: With the use of PECO air purification technology, self reported asthma scores decreased significantly. Future studies with increased patient numbers and objective asthma endpoints are planned to confirm these findings.