423:
Association between atopic march and asthma morbidity
Sunday, March 4, 2018
South Hall A2 (Convention Center)
Ejaz Yousef, MD FAAAAI, Emily Hoehn, RN
RATIONALE:

Atopic dermatitis (AD) is often the first step in the atopic march leading to the development of asthma. The goal of this study was to evaluate the relationship between atopic march and asthma related hospitalizations and use of oral steroids

METHODS:

Data on 247 asthmatic children aged 3-18 years were collected. The study subjects were divided into two groups. Group A (N= 136) comprised of asthmatic children with history of atopic dermatitis. Subjects in Group B (N= 111) were children without history of atopic dermatitis. We compared the rate of hospitalizations and use of oral steroids between asthmatic children with atopic march and those without coexisting atopic march. Patients were adjusted for the severity of their asthma based on symptoms documented at their first visit to the asthma specialist per the NAEPP guidelines

RESULTS:

Group A: 154 courses of oral steroids were prescribed for the subjects in Group A. Average intake of oral steroid /year/patient was 1.15. Eighty asthma related hospital admissions were recorded for all the patients in Group A. Average number of hospitalization/patient in this group was 0.59

Group B: 71 courses of oral steroids were prescribed for the subjects in Group B. Average intake of oral steroid/year/patient was 0.64. Only 18 asthma related hospital admissions were recorded for all the patients in Group B. Average number of hospitalization/patient in this group was 0.16

CONCLUSIONS:

Children with atopic march and asthma were associated with increased hospitalization and steroid use and may serve as early markers for increased asthma morbidity