317:
Peak oral and nasal inspiratory flows in asthmatics from a low income community in Rio de Janeiro, Brazil.
Sunday, March 4, 2018
South Hall A2 (Convention Center)
Marta Machado, Andrea Venerabile, Aniela Bonorino Xexeo Castelo Branco, Eliane Fonseca
RATIONALE: Peak oral (POIF) and nasal (PNIF) inspiratory flows are lacking of consistent published studies. Evaluate nasal and lung flows patency by these methods can open new perspectives of a detailed diagnosis, and, by consequence, a more precise asthma/rhinitis treatment and monitoring.

METHODS: Retrospective data and analysis of charts of asthmatics children and adolescents treated from February to December 2016, in a low income primary health care center. We collected detailed demographic data, the presence of rhinitis according to ARIA, nutritional status, blood pressure, thoracic deformity, growth rate, classification of asthma and bronchodilator (BD) response evaluated by POFI and PEF. We performed PNIF before and after 3 months of nasal corticosteroid treatment. Statistical analysis were performed using SSPS 20.

RESULTS: From 146 asthmatics studied, 82(56,2%) were male, median age 11,5 years old. All of them performed a POIF. 61(42%) presented a positive BD response on POIF, but 21 (34%) presented a negative BD response on PEF. Performed PNIF 68 subjects (46,6%) and 52 (76,5%) had persistent rhinitis. 57 (83,8%) obtained results ≤ 80% expected. Asthmatic patients with persistent rhinitis are 6 times more likely to have low PFIN (p <0.05 and X2 = 6,113). From 22 (32,3%) subjects performing PNFI before and after 3 months of nasal corticosteroid treatment, 17 (77,3%) presented an increment of ≥ 15% on PNIF. A significant correlation between persistent rhinitis and low PNIF was observed (p<0,05 e X2=6,113).

CONCLUSIONS: The use of both POIF and PNIF could be of interest to manage subjects with asthma and rhinitis.