699:
Epidemiology and Risk Factors of Allergic Diseases in Adolescents
Monday, March 5, 2018
South Hall A2 (Convention Center)
Cristine S. Rosario, MD, Cristina a Cardozo, Debora C Chong e Silva, Herberto J. Chong Neto, MD PhD FAAAAI, Carlos a Riedi, Nelson Augusto Rosario, MD PhD FAAAAI
RATIONALE: ISAAC (International Study of Asthma and Allergies in Childhood), assessed epidemiological data on allergic diseases was not addressed to allergic conjunctivitis.

METHODS: ISAAC questionnaire was filled by 4,520 adolescents 13-14y/o from Curitiba, Brazil. Specific allergic conjunctivitis questions were added to the questionnaire. Four hundred and seventy-two students were submitted to allergic skin testing (AST) and answered a supplementary questionnaire on family history, immunization status, infectious diseases, environmental conditions and diet.

RESULTS: The prevalence of asthma was 17.5%, medical diagnosis of asthma 13.2%, rhinitis 34.7%, rhinoconjunctivitis:20.1%, medical diagnosis of rhinitis 51.1%, atopic eczema 5.9% and medical diagnosis of eczema 13.2%, allergic conjunctivitis 15.5%. There was an association between asthma, rhinoconjunctivitis, atopic eczema and allergic conjunctivitis in 1.3% of adolescents. Risk factors were father with asthma, (OR = 3.18; CI95% 1.24-7.95), mother with asthma (OR = 2.92; CI95% 1.36-6.09), symptoms of eczema (OR = 2.38; CI95% 1.28- 4.35) and allergic conjunctivitis (OR = 3.12; CI95% 1.67-5.88), AST positive for Blomia tropicalis (OR = 2.66; CI95% 1.49-4.92) and presence of humidity at home (OR = 1.85; CI95% 1.07- 3.19). Among the 85 students with asthma, 82.3% had positive AST, being 11.7% monosensitized and 70.5% polysensitized. Among the 387 participants without asthma, 64.3% had positive AST, 11.9% monosensitized and 52.4% polysensitized.

CONCLUSIONS: Prevalence of asthma is high in Curitiba. Risk factors were atopy in family, symptoms of eczema and allergic conjunctivitis, positive AST for Blomia tropicalis and presence of humidity at home. Sensitization rate in both groups was high.