METHODS: Retrospective study of the electronic medical record of adults outpatients with CSU, attended at a tertiary hospital between 2000 and 2016. The presence of AID or autoantibodies concomitant with CSU and if CSU diagnosis preceded or followed AID were assessed.
RESULTS: This study assessed 988 patients with CSU. AID and/or autoantibodies were present in 143 patients (14.5%). Of these, 88.1% were female, the mean age was 53.3 years and the mean time of CSU was 12.1 years. Of the 143 patients, 64 (44.8%) had AIDs, the most prevalent were hypothyroidism or hyperthyroidism. Autoantibodies without AID were present in 79 patients (55.2%). CSU preceded (mean time of 11.5 years) the diagnosis of AID in 24 patients (37.5%) and CSU developed after AID diagnosis (mean time of 5 years) in 29 patients (45.3%). CSU concomitant to AID was diagnosed in 11 patients (17.2%).
CONCLUSIONS: The link between CSU and AID isn’t yet fully understood, however, several studies showed a high prevalence of this association. In this study, the association between CSU and AID and/or autoantibodies was observed in 14.5% of the patients over a 16-year period.