The Epithelium as Boss: Lessons from the AADCRC

3308:

Immune Mechanisms

Sunday, March 4, 2018: 10:45 AM-12:00 PM

Convention Center, South Concourse, Level 3, S310AB

1.25 CME/CE

Symposium

Primary Moderators:

Mubeccel Akdis, MD PhD

Alkis Togias, MD FAAAAI

Learning Objectives:

Describe the mechanisms by which the major airway mucins MUC5AC and MUC5B are organized within the mucus gel and how this gel contributes to airway obstruction in asthma
Describe the endogenous pathway that normally curtails the development of Th2 immunity at the squamous mucosa mediated by the serine protease inhibitor SPINK7, whose loss of function is involved in unleashing marked Th2 related responses
Describe the role of surfactant protein A in regulating allergic airway disease

10:45 AM

Airway Epithelial Reprogramming in Asthma
David Erle, MD

11:05 AM

Question & Answer

11:10 AM

Regulation of IL-13 By Surfactant Protein A2 in Asthma
Monica Kraft, MD FAAAAI

11:30 AM

Question & Answer

11:35 AM

SPINK7 in Allergic Inflammation
Marc E Rothenberg, MD PhD FAAAAI

11:55 AM

Question & Answer

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