3308:
The Epithelium as Boss: Lessons from the AADCRC
Immune Mechanisms
Sunday, March 4, 2018: 10:45 AM-12:00 PM
Convention Center, South Concourse, Level 3, S310AB
1.25 CME/CE
Symposium
Primary Moderators:
Mubeccel Akdis, MD PhD
Alkis Togias, MD FAAAAI

Learning Objectives:
  1. Describe the mechanisms by which the major airway mucins MUC5AC and MUC5B are organized within the mucus gel and how this gel contributes to airway obstruction in asthma
  2. Describe the endogenous pathway that normally curtails the development of Th2 immunity at the squamous mucosa mediated by the serine protease inhibitor SPINK7, whose loss of function is involved in unleashing marked Th2 related responses
  3. Describe the role of surfactant protein A in regulating allergic airway disease
10:45 AM
Airway Epithelial Reprogramming in Asthma
David Erle, MD
11:05 AM
Question & Answer
11:10 AM
Regulation of IL-13 By Surfactant Protein A2 in Asthma
Monica Kraft, MD FAAAAI
11:30 AM
Question & Answer
11:35 AM
SPINK7 in Allergic Inflammation
Marc E Rothenberg, MD PhD FAAAAI
11:55 AM
Question & Answer
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